Massive Ringerʼs Lactate Infusion

Spectrophotometric determination of ethacridine lactate in infusion

AIM A simple, rapid, selective, accurate, and precise UV spectrophotometric method has been developed for the estimation of ethacridine lactate from bulk and pharmaceutical formulation. MATERIALS AND METHODS Appropriate aliquot portions of stock standard solution of ethacridine lactate were transferred into five separate 10 ml volumetric flasks, and the volume was adjusted to the mark with do...

Massive thrombosis produced by fatty acid infusion.

CRITICAL CARE Effect of site of lactate infusion on regional lactate exchange in pigs

Key points † This study addresses the uptake of lactate after central venous or portal infusion in pigs. † Lactate metabolism is important for understanding the haemodynamics and regional blood flow of sepsis. † Lactate infused into the portal vein is removed mainly by the liver, whereas central venous infusion results in less uptake by the liver. Background. The rate of extra-hepatic lactate p...

Effect of site of lactate infusion on regional lactate exchange in pigs.

BACKGROUND The rate of extra-hepatic lactate production and the route of influx of lactate to the liver may influence both hepatic and extra-hepatic lactate exchange. We assessed the dose-response of hepatic and extra-hepatic lactate exchange during portal and central venous lactate infusion. METHODS Eighteen pigs randomly received either portal (n=5) or central venous (n=7) lactate infusion ...

Prandial lactate infusion inhibits spontaneous feeding in rats.

To investigate the acute effects of lactate on spontaneous feeding, we infused lactate in the hepatic portal vein (0.5, 1.0, and 1.5 mmol lactate/meal) or in the vena cava (1.0 and 1.5 mmol lactate/meal) of ad libitum-fed rats during their first spontaneous nocturnal meal. Infusions (5 min, 0.1 ml/min) were remotely controlled, and a computerized feeding system recorded meal patterns. In separa...